How Fast Can Thiols Bind to the Gold Nanoparticle Surface?

Bard, Amanda; Rondon, Rebeca; Marquez, Daniela T.; Lanterna, Anabel E.; Scaiano, Juan C.

Abstract

Kinetics of gold nanoparticle surface modification with thiols can take more than one hour for completion. 7‐mercapto‐4‐methylcoumarin can be used to follow the process by fluorescence spectroscopy and serves as a convenient molecular probe to determine relative kinetics. SERS studies with aromatic thiols further support the slow surface modification kinetics observed by fluorescence spectroscopy. The formation of thiolate bonds is a relatively slow process; we recommend one to two hour wait for thiol binding to be essentially complete, while for disulfides, overnight incubation is suggested.

Citation

Bard, A., Rondon, R., Marquez, D. T., Lanterna, A. E., & Scaiano, J. C. (2018). How Fast Can Thiols Bind to the Gold Nanoparticle Surface?. Photochemistry and Photobiology, 94(6), 1109-1115. https://doi.org/10.1111/php.13010

• Journal Article Type: Article
• Acceptance Date: Sep 7, 2018
• Online Publication Date: Oct 13, 2018
• Publication Date: 2018-11
• Deposit Date: Jun 22, 2020
• Publicly Available Date: Jul 21, 2020
• Journal: Photochemistry and Photobiology
• Print ISSN: 0031-8655
• Publisher: Wiley
• Peer Reviewed: Peer Reviewed
• Volume: 94
• Issue: 6
• Pages: 1109-1115
• DOI: https://doi.org/10.1111/php.13010
• Keywords: Physical and Theoretical Chemistry; Biochemistry; General Medicine
• Public URL: https://nottingham-repository.worktribe.com/output/4442828
• Publisher URL: https://onlinelibrary.wiley.com/doi/abs/10.1111/php.13010